alexa [Adherence to HAART, quality of life and psychopathological symptoms among HIV AIDS infected patients].
Infectious Diseases

Infectious Diseases

Journal of AIDS & Clinical Research

Author(s): Margalho R, Pereira M, Ouakinin S, Canavarro MC, Margalho R, Pereira M, Ouakinin S, Canavarro MC

Abstract Share this page

Abstract OBJECTIVES: Patient adherence to highly active antiretroviral therapy (HAART) is essential to treatment success, and improved quality of life (QoL) and mental health have been recognized as important outcomes from the HIV treatment. However, very few published research studies have related these domains to HAART adherence. The purpose of this study was to examine the association between adherence to HAART, QoL and psychopathological symptoms in a sample of HIV-infected patients, and to identify demographic, clinical and psychological predictors of non-adherence. METHODS: A cross-sectional study was conducted in the main services/departments of infectious diseases of Portuguese Hospitals. The sample consisted of 762 HIV-infected patients. The assessment protocol included the Portuguese versions of the WHOQOLHIV-Bref and the Brief Symptom Inventory (BSI). RESULTS: Of the 762 patients, 133 (17.5\%) reported not to fully adhere to HIV medication. Non-adherent patients reported significantly lower QoL. Follow-up tests reported significant differences in four of six domains, with the exception of Social relationships and Spirituality domains. Regarding psychopathological symptoms, there was also a significant effect. Follow-up tests reported a significant difference only on psychoticism. In multivariate logistic regression, younger individuals, people diagnosed and on medication for longer time, with lower CD4+ T cell count, on symptomatic/AIDS stage and with higher scores on interpersonal sensitivity, anxiety and psychoticism were more likely to be non-adherents. CONCLUSIONS: Future studies assessing HAART adherence should consider the interplay of demographic and HIV-related variables, as well as psychological status. Also, it may help to elicit those people who are at risk for non-adherence, as well as poorer quality of life and mental health.
This article was published in Acta Med Port and referenced in Journal of AIDS & Clinical Research

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords