alexa Adult neurogenesis and its alteration under pathological conditions.


Journal of Neurology & Neurophysiology

Author(s): Kaneko N, Sawamoto K, Kaneko N, Sawamoto K

Abstract Share this page

Abstract Even in the adult brain, neural stem cells in the dentate gyrus and subventricular zone continue to produce neuronal precursors, which migrate and differentiate into functional mature neurons. This physiological neurogenesis is thought to be involved in neuronal plasticity. Moreover, recent studies indicate that adult neurogenesis can change in response to various brain insults, including psychiatric diseases, stroke, and neurodegenerative disorders. Although increased neurogenesis in these pathological conditions could contribute to the restoration and regeneration of the damaged brain, an inadequate and/or excessive supply of new neurons, or suppressed neurogenesis, could contribute to their pathophysiology. To develop successful regenerative treatments for the injured brain, we need to understand more precisely and comprehensively the mechanisms regulating adult neurogenesis under both physiological and pathological conditions. This article was published in Neurosci Res and referenced in Journal of Neurology & Neurophysiology

Relevant Expert PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version