alexa Aggregation of features of the metabolic syndrome is associated with increased prevalence of chronic complications in Type 2 diabetes.
Diabetes & Endocrinology

Diabetes & Endocrinology

Journal of Diabetes & Metabolism

Author(s): Costa LA, Canani LH, Lisba HR, Tres GS, Gross JL

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Abstract AIMS: To investigate the association of features of the metabolic syndrome with the prevalence of chronic complications. METHODS: A cross-sectional study was conducted with 548 patients with Type 2 diabetes mellitus (DM). Metabolic syndrome was diagnosed in the presence of at least two of the following: hypertension, dyslipidaemia, obesity, and microalbuminuria. RESULTS: Patients with the metabolic syndrome (85\%) had a higher prevalence of peripheral vascular disease (PVD) (35\% vs. 18\%), retinopathy (44\% vs. 20\%), distal sensory neuropathy (DSN) (44\% vs. 24\%), micro- and macroalbuminuria (38\% vs. 28\%) and coronary artery disease (CAD) (53\% vs. 36\%). The more metabolic syndrome features (none/one, two, three or four), the higher the proportion of diabetes complications: PVD 18\%, 31\%, 37\% and 38\%; stroke 1.0\%, 4.5\%, 5.9\% and 11.3\%; retinopathy 20\%, 38\%, 42\% and 64\%; DSN 24\%, 32\%, 49\% and 57\%; micro- and macroalbuminuria 28\%, 36\% and 41\%; and CAD 36\%, 44\%, 52\% and 60\% (P < 0.05). CONCLUSIONS: The metabolic syndrome and the aggregation of its components were significantly associated with macro- and microvascular complications in Type 2 DM patients.
This article was published in Diabet Med and referenced in Journal of Diabetes & Metabolism

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