Author(s): Thorne BM, Donohoe T, Lin KN, Lyon S, Medeiros DM, , Thorne BM, Donohoe T, Lin KN, Lyon S, Medeiros DM,
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Abstract A variety of behaviors was measured in adult Long-Evans male rats fed ground rat chow containing either no added aluminum, low aluminum (1500 mg/kg), moderate aluminum (2500 mg/kg), or high aluminum (3500 mg/kg). There were no effects of aluminum on either body weight or mouse killing. There was an inverse relationship between brain aluminum and open-field activity. Elevated brain aluminum was correlated with relatively poor performance on a single-trial passive-avoidance task and on a visual discrimination with reversal task.
This article was published in Physiol Behav
and referenced in Journal of Drug Metabolism & Toxicology