alexa Amezinium. Synthesis and radioactive labelling.
Pharmaceutical Sciences

Pharmaceutical Sciences

Pharmaceutica Analytica Acta

Author(s): Reicheneder F, Burger TF, Knig H, Kropp R, Lietz H,

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Abstract The synthesis of the novel pharmacologically active substance 4-amino-6-methoxy-1-phenyl-pyridazinium methyl sulfate (ameziniummetilsulfate, LU 1631, Regulton) and the proof of its structure are described. In addition the present paper deals with the microsynthesis of samples which are labelled at a definite site with 14C or 3H, respectively, and which are needed for the examination of its metabolism and the pharmacokinetics.
This article was published in Arzneimittelforschung and referenced in Pharmaceutica Analytica Acta

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