alexa Amphotericin B and its delivery by liposomal and lipid formulations.
Materials Science

Materials Science

Journal of Nanomedicine & Nanotechnology

Author(s): Gates C, Pinney RJ

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Abstract In recent years, new formulations of the original amphotericin B preparation (Fungizone) have been devised in order to overcome toxicity problems that frequently occur. These preparations represent an improved method of drug delivery, with an increased therapeutic index and a decrease in toxicity to mammalian cell membranes. The new formulations have different physico-chemical characteristics and differ in pharmacokinetic parameters. Their effects must be compared with conventional amphotericin B to ascertain potential roles in future antifungal therapy.
This article was published in J Clin Pharm Ther and referenced in Journal of Nanomedicine & Nanotechnology

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