alexa An atypical verrucous carcinoma of the tongue arising in a patient with oral lichen planus associated with hepatitis C virus infection.


JBR Journal of Interdisciplinary Medicine and Dental Science

Author(s): Carrozzo M, Carbone M, Gandolfo S, Valente G, Colombatto P,

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Abstract Recently, a clinical relationship between oral lichen planus (OLP) and hepatitis C virus (HCV) infection has been suggested, but the role of this virus on the course of OLP is unknown. We report an unusual lingual localisation of verrucous carcinoma arising in a patient with histologically confirmed OLP and HCV infection diagnosed with second generation enzyme-linked immunosorbent assay and recombinant immunoblot assay. Serum HCV-RNA detected using nested reverse transcriptase polymerase chain reaction (RT-PCR) confirm HCV replication. No classical risk factors associated with verrucous carcinoma were present.
This article was published in Oral Oncol and referenced in JBR Journal of Interdisciplinary Medicine and Dental Science

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