alexa An evaluation of thrombophilia screening in an urban tertiary care medical center: A "real world" experience.
Haematology

Haematology

Journal of Hematology & Thromboembolic Diseases

Author(s): Somma J, Sussman II, Rand JH

Abstract Share this page

Abstract To evaluate the utilization of thrombophilia screening at a large urban academic tertiary care center, we retrospectively examined the indications, appropriateness, and results of 200 consecutive thrombophilia panels. Of the panels, 103 (51.5\%) were ordered for venous thromboembolism; 124 (62.0\%) were ordered during acute thrombotic episodes, and at least 40 (20.0\%) had abnormal protein C and S results, of which 25 (63\%) were attributable to anticoagulation and the remainder to pregnancy. Of the 200 panels, 46 (23.0\%) had a significant abnormality; the most common abnormal result was a lupus anticoagulant, occurring in 23 cases (11.3\%). Thrombophilia screening seems to be overutilized in our population, especially considering that the majority of tests are ordered during suboptimal conditions, eg, acute thrombosis, pregnancy, or anticoagulation. At present, outside the research setting, thrombophilia panels should be reserved for special circumstances, targeted to factors for which there would be a specific clinical impact, and performed in the absence of confounding clinical variables. This article was published in Am J Clin Pathol and referenced in Journal of Hematology & Thromboembolic Diseases

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords