alexa An update of cancer incidence in the Agricultural Health Study


Occupational Medicine & Health Affairs

Author(s): Stella Koutros, Michael CR Alavanja, Jay H Lubin

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Objective: Our objective is to re-evaluate cancer incidence among Agricultural Health Study participants.

Methods: Standardized incidence ratios (SIR) and Relative Standardized Ratios were calculated.

Results: A significant excess of prostate cancer was seen for private and commercial applicators, SIR = 1.19 (95% Confidence Interval (CI) 1.14, 1.25) and SIR = 1.28 (95% CI 1.00, 1.61), respectively. Excesses were observed for lip cancer, SIR = 1.97 (95% CI 1.02, 3.44), and multiple myeloma, SIR = 1.42 (95% CI 1.00, 1.95) among private applicators from North Carolina and for marginal zone lymphoma among Iowa spouses, SIR = 2.34 (95% CI 1.21, 4.09).

Conclusions: While lower rates of smoking and increased physical activity probably contribute to the lower overall cancer incidence, agricultural exposures including pesticides, viruses, bacteria, sunlight, and other chemicals may increase risks for specific cancer sites.

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This article was published in Journal of Occupational and Environmental Medicine and referenced in Occupational Medicine & Health Affairs

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