Author(s): Cahlkov L, Kulhnkov A, Urbanov K, Valterov I, Mackov K,
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Abstract From the bulbs of Zephyranthes robusta Baker (Amaryllidaceae), seven known compounds, belonging to four structural types of Amaryllidaceae alkaloids, were identified and quantified by GC-MS. The alkaloid extract from the bulbs showed promising acetylcholinesterase and butyrylcholinesterase inhibitory activities against HuAChE (IC50 = 35.9 +/- 3.5 microg/mL) and HuBuChE (IC50 = 190.9 +/- 8.2 microg/mL).
This article was published in Nat Prod Commun
and referenced in Medicinal & Aromatic Plants