Author(s): Dmitrovic J, Chan SC, Chan SH
Abstract Share this page
Abstract This paper describes a simple procedure for the quantitative analysis of 25 polychlorinated biphenyl congeners (PCB) in serum. They are PCB 70, 74, 77, 87, 99, 101, 118, 126, 128, 138, 151, 153, 156, 169, 170, 180, 183, 187, 191, 194, 205, 206, 208 and 209. In addition, 15 pesticides are analyzed in the same extract: aldrin, p,p'-DDE, p,p'-DDT, dieldrin, endrin, endosulfan I, heptachlor, hexachlorobenzene, alpha-hexachlorocyclohexane, beta-hexachlorocyclohexane, lindane, methoxychlor, mirex, pentachlorobenzene, and 1,2,3,4-tetrachlorobenzene. The procedure involved sample cleanup using a combination of C18 and NH(2) solid phase extraction cartridges. The instrumental technique was gas chromatography/mass spectrometry with both electron ionization and negative chemical ionization in the selected ion monitoring mode. Concentration of sub-ng/ml level was attainable with 2 ml of serum sample.
This article was published in Toxicol Lett
and referenced in Journal of Chromatography & Separation Techniques