Author(s): Bardor M, Cabrera G, Rudd PM, Dwek RA, Cremata JA,
Abstract Share this page
Abstract Plants are attractive hosts for the production of recombinant proteins. However, their inability to process authentic human N-glycan structures imposes a major limitation on their use as expression systems for therapeutic products. Several strategies have emerged to engineer plant N-glycans into human-compatible molecules. In this context, fast and reliable analytical strategies for the identification of plant N-glycan profiles have been developed to define the N-glycosylation pathways of crops, to monitor the production of plant-made pharmaceuticals and to assess in planta remodelling strategies.
This article was published in Curr Opin Struct Biol
and referenced in