alexa Animal models of diabetes.
Diabetes & Endocrinology

Diabetes & Endocrinology

Journal of Diabetes & Metabolism

Author(s): Mordes JP, Rossini AA

Abstract Share this page

Abstract Spontaneous diabetes is a common occurrence in many animal species. In addition, animals can be rendered diabetic by a wide variety of experimental procedures. Diabetic animals may be regarded as models of the disease in man. However, such animals display a wide diversity of pathophysiology, and, in fact, no animal syndrome corresponds precisely to any type of diabetes in human subjects. The most common diabetes syndromes in animals occur in the context of obesity, hyperinsulinemia and insulin resistance. Many such syndromes remit spontaneously. Dietary restriction and weight reduction effectively reverse some of these syndromes, but in other cases only partial correction of the syndrome occurs. Diabetes in lean animals is less common. The diabetes of lean animals is more frequently characterized by hypoinsulinemia, ketosis and insulin dependence than is the case with obese animals. Diabetes may be produced experimentally by means of surgery, viral infection or the administration of various hormones and chemical agents. Both the spontaneous and experimental animal models have been used effectively to study the etiologies, complications, treatments and prevention of diabetes.
This article was published in Am J Med and referenced in Journal of Diabetes & Metabolism

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version