alexa Animal models of substance abuse and addiction: implications for science, animal welfare, and society.
Psychiatry

Psychiatry

Journal of Addiction Research & Therapy

Author(s): Lynch WJ, Nicholson KL, Dance ME, Morgan RW, Foley PL

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Abstract Substance abuse and addiction are well recognized public health concerns, with 2 NIH institutes (the National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism) specifically targeting this societal problem. As such, this is an important area of research for which animal experiments play a critical role. This overview presents the importance of substance abuse and addiction in society; reviews the development and refinement of animal models that address crucial areas of biology, pathophysiology, clinical treatments, and drug screening for abuse liability; and discusses some of the unique veterinary, husbandry, and IACUC challenges associated with these models.
This article was published in Comp Med and referenced in Journal of Addiction Research & Therapy

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