Author(s): Ghoshal S, Prasad BN, Lakshmi V
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Abstract The fruits of Piper longum used in traditional remedies against intestinal distress have been tested for their efficacy against experimental caecal amoebiasis of rats. The ethanolic extract, hexane fraction, n-butanol soluble fraction exerted in vitro amoebicidal action at 1000 micrograms/mL and the chloroform fraction at 500 micrograms/mL. The ethanolic extract and piperine, a pure compound, from this plant material cured 90\% and 40\% of rats with caecal amoebiasis, respectively.
This article was published in J Ethnopharmacol
and referenced in Medicinal Chemistry