alexa Anti-androgenic activity of Myricae Cortex--isolation of active constituents from bark of Myrica rubra.
Environmental Sciences

Environmental Sciences

Journal of Biodiversity, Bioprospecting and Development

Author(s): Matsuda H, Yamazaki M, Matsuo K, Asanuma Y, Kubo M

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Abstract The aqueous ethanol extract of Myricae Cortex (bark of Myrica rubra Sieb. et Zucc., Myricaceae) showed in vitro testosterone 5alpha-reductase inhibitory activity and in vivo anti-androgenic activity using growth of flank organ in castrated Syrian hamsters and/or hair regrowth after shaving in testosterone-treated C57Black/6CrSlc mice. Three constituents, myricanone, myricanol, and myricetin were identified as the main active principles.
This article was published in Biol Pharm Bull and referenced in Journal of Biodiversity, Bioprospecting and Development

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