alexa ANTIBACTERIAL ACTION OF ZINC OXIDE NANOPARTICLES AGAINST FOODBORNE PATHOGENS
Immunology

Immunology

Immunome Research

Author(s): Ahmed A Tayel, Wael FEL Tras, Shaaban Moussa, Ashraf F ELBaz, Hoda Mahrus

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The current spreading of nanomaterial applications supports the search for further possible functions of theses diminutive particles. The antibacterial potentiality of zinc oxide (ZnO) nanoparticles (NPs), compared with conventional ZnO powder, against nine bacterial strains, mostly foodborne including pathogens, was evaluated using qualitative and quantitative assays. ZnO NP was more efficient as antibacterial agent than powder. Gram-positive bacteria were generally more sensitive to ZnO than Gram negatives. The exposure of Salmonella typhimurium and Staphylococcus aureus to their relevant minimal inhibitory concentrations from ZnO NP reduced the cell number to zero within 8 and 4 h, respectively. Scanning electron micrographs of the treated bacteria with NPs exhibited that the disruptive effect of ZnO on S. aureus was vigorous as all treated cells were completely exploded or lysed after only 4 h from exposure. Promising results of ZnO NP antibacterial activity suggest its usage in food systems as preservative agent after further required investigations and risk assessments. PRACTICAL APPLICATIONS Foodborne pathogen invasion is still a recurrent serious problem facing researchers and food industry overseers. The introduction of novel powerful antimicrobial agents is of great importance for the control of pathogenic bacteria, especially antibiotic-resistant strains. Zinc oxide (ZnO) nanoparticle (NP) could be one of these potential alternatives. This study focused on ZnO NP because of its increasing presence in many marketable products and that supports its application in food industries as a reasonably safe agent. The demonstrated antibacterial activity of ZnO NP recommends its possible application in the food preservation field; otherwise it can be applied as a potent sanitizing agent for disinfecting and sterilizing food industry equipment and containers against the attack and contamination with foodborne pathogenic bacteria.

This article was published in journal of food safety and referenced in Immunome Research

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