alexa Anticoagulation policy after venous resection with a pancreatectomy: a systematic review.


Surgery: Current Research

Author(s): Chandrasegaram MD, Eslick GD, Lee W, BrookeSmith ME, Padbury R,

Abstract Share this page

Abstract BACKGROUND: Portal vein (PV) resection is used increasingly in pancreatic resections. There is no agreed policy regarding anticoagulation. METHODS: A systematic review was performed to compare studies with an anticoagulation policy (AC+) to no anticoagulation policy (AC-) after venous resection. RESULTS: There were eight AC+ studies (n = 266) and five AC- studies (n = 95). The AC+ studies included aspirin, clopidogrel, heparin or warfarin. Only 50\% of patients in the AC+ group received anticoagulation. There were more prosthetic grafts in the AC+ group (30 versus 2, Fisher's exact P < 0.001). The overall morbidity and mortality was similar in both groups. Early PV thrombosis (EPVT) was similar in the AC+ group and the AC- group (7\%, versus 3\%, Fisher's exact P = 0.270) and was associated with a high mortality (8/20, 40\%). When prosthetic grafts were excluded there was no difference in the incidence of EPVT between both groups (1\% vs 2\%, Fisher's exact test P = 0.621). CONCLUSION: There is significant heterogeneity in the use of anticoagulation after PV resection. Overall morbidity, mortality and EPVT in both groups were similar. EPVT has a high associated mortality. While we have been unable to demonstrate a benefit for anticoagulation, the incidence of EPVT is low in the absence of prosthetic grafts. © 2013 International Hepato-Pancreato-Biliary Association.
This article was published in HPB (Oxford) and referenced in Surgery: Current Research

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

  • Rheumatology and Arthritis Surgeons Meeting
    October 2-4, 2017 Las Vegas , USA
  • 3rd International Conference on Spinal Surgery
    October 16-18, 2017, Chicago, USA
  • Global surgeons meeting on Bariatric surgery
    October 30-November 1, 2017,San Antonio,USA

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version