alexa Antifungal flavanones and prenylated hydroquinones from Piper crassinervium Kunth.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Molecular and Genetic Medicine

Author(s): Danelutte AP, Lago JH, Young MC, Kato MJ

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Abstract Bioactivity-guided fractionation of the EtOAc extract from leaves of Piper crassinervium yielded three prenylated hydroquinones together with two known flavanones naringenin and sakuranetin. Their structures were determined by means of spectroscopic analysis (NMR, IR, UV and MS) including two-dimensional NMR spectroscopy experiments (1H-1H COSY, HMQC, HMBC and NOESY). The antifungal activity was determined by direct bioautography against Cladosporium cladosporioides and C. sphaerospermum.
This article was published in Phytochemistry and referenced in Journal of Molecular and Genetic Medicine

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