alexa Anti-ganglioside antibodies in patients with Guillain Barré syndrome and other neurological disorders.


Journal of Neurology & Neurophysiology

Author(s): Vaishnavi C, Behura C, Prabhakar S, Sharma A, Kharbanda P, Vaishnavi C, Behura C, Prabhakar S, Sharma A, Kharbanda P

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Abstract A study was performed on 59 Guillain-Barré syndrome (GBS) cases, 58 neurological controls (NC) and 60 non-neurological controls (NNC) to investigate the association of anti-ganglioside antibodies in GBS and other neurological disorders. Campylobacter jejuni was isolated from 5.7\% of GBS patients. Anti-ganglioside immunoglobulin G was present in 82\% and immunoglobulin M in 46\% in acute inflammatory demyelinating polyneuropathy patients, 70\% and 44\% respectively in acute motor axonal neuropathy subgroup and 38\% each in acute motor sensory axonal neuropathy subgroup. Though high intensity of anti-gangliosides was present in the GBS patients, the NC patients also had adequate anti-gangliosides compared with the NNC group. This article was published in Indian J Med Microbiol and referenced in Journal of Neurology & Neurophysiology

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