Author(s): Rathi A, Rao ChV, Ravishankar B, De S, Mehrotra S
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Abstract The water decoction of root and aerial parts of Desmodium gangeticum (Leguminosae) was examined for anti-inflammatory and anti-nociceptive activity in experimental animals. The root and aerial decoction in doses of 5, 10 and 20 mg /kg caused a dose-dependent inhibition of swelling caused by carrageenin equivalent to 14.58-51.02\% protection and 14.43-38.67\%, respectively, in cotton pellet granuloma. There was a significant increase in analgesio-meter-induced force equivalent to 6.56-67.66\% protection and 22.18-73.83\% protection in acetic acid-induced writhing. The result establishes the traditional use of water decoction of Desmodium gangeticum codified in Indian System of Medicine.
This article was published in J Ethnopharmacol
and referenced in Pharmaceutica Analytica Acta