Author(s): SSSudha, RKarthic, JRengaramanujam, Athulya
The screening of antioxidant and antimicrobial potentiality of Spirulina platensis and Aphanothece sp against multidrug resistant pathogens were investigated using standard microbiological techniques and antioxidant is d etermined by FRAP and DP PH . The intracellular and extra cellular extr acts were tested by agar well diffusion method for activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa , Klebsiella s p, Proteus sp and Embedobacter sp. isolated from clinical samples. The susceptibility patterns of the test isol ates against the extract intracellular and extra cellular was determined . The result showed that no significant antibacterial activity by Aphanothece sp, in contrast intracellular extracts of S.platensis produce antibacterial activity against above mention ed strains and S.platensis have more antioxidant activity than Aphanothece sp . The observed antibacterial effects were believed to be due to the presence of alkaloids, tannins, and flavonoids identified in the extracts. The results apparently justified the ir use in the treatment of infections .