alexa Antimicrobial and cytotoxicity evaluation of Buchholzia coriacea stem bark.
Pharmaceutical Sciences

Pharmaceutical Sciences

Biochemistry & Pharmacology: Open Access

Author(s): Ajaiyeoba EO, Onocha PA, Nwozo SO, Sama W

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Abstract Fractions prepared from the methanol extract of Buchholzia coriacea stem bark exhibited a high concentration-dependent antibacterial and antifungal activity compared to the standard antibiotics, ampicillin and tioconazole. In the brine shrimp lethality (BSL) assay, the methanol extract was found to be non-toxic with an LC(50) of 1031 microg/ml. The two main compounds present in the most active fraction were isolated and identified as lupeol and beta-sitosterol.
This article was published in Fitoterapia and referenced in Biochemistry & Pharmacology: Open Access

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