alexa Antimicrobial peptides: clinical relevance and therapeutic implications.


Journal of Blood Disorders & Transfusion

Author(s): Pinheiro da Silva F, Machado MC

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Abstract Antimicrobial peptides (AMPs) are molecules that provide protection against environmental pathogens, acting against a large number of microorganisms, including bacteria, fungi, yeast, virus and others. Two major groups of antimicrobial peptides are found in humans: cathelicidins and defensins. Recently, several studies have furnished information that besides their role in infection diseases, antimicrobial peptides play a role in diseases as diverse as inflammatory disorders, autoimmunity and cancer. Here, we discuss the role of antimicrobial peptides and vitamin D have in such complex diseases and propose their use should be more explored in the diagnosis and treatment of such conditions. Copyright © 2012 Elsevier Inc. All rights reserved. This article was published in Peptides and referenced in Journal of Blood Disorders & Transfusion

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