alexa Antiretroviral therapy with tenofovir is associated with mild renal dysfunction.
Pharmaceutical Sciences

Pharmaceutical Sciences

Journal of Pharmacogenomics & Pharmacoproteomics

Author(s): Mauss S, Berger F, Schmutz G

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Abstract A cross-sectional study was conducted to compare patients treated with tenofovir with patients never treated with tenofovir. Patients on tenofovir showed a lower mean glomerular filtration rate estimated by creatinine clearance or cystatin C clearance compared with control patients. In total, 24 patients on tenofovir versus five control patients had proteinuria greater than 130 mg/day. In the majority of patients on tenofovir proteinuria was of tubular origin.
This article was published in AIDS and referenced in Journal of Pharmacogenomics & Pharmacoproteomics

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