alexa Anxiety, depression and personality traits in severe, prednisone-dependent asthma.
Immunology

Immunology

Journal of Clinical & Cellular Immunology

Author(s): Amelink M, Hashimoto S, Spinhoven P, Pasma HR, Sterk PJ,

Abstract Share this page

Abstract BACKGROUND: Anxiety and depression are prevalent in patients with asthma, and associated with more exacerbations and increased health care utilization. Since psychiatric intervention might improve asthma control, we examined whether patients with severe, prednisone-dependent asthma are at higher risk of these disorders than patients with severe non-prednisone dependent asthma or mild-moderate asthma, and whether they exhibit different personality traits. METHODS: Sixty-seven adults with severe prednisone-dependent asthma, 47 with severe non-prednisone dependent and 73 patients with mild-moderate asthma completed the HADS depression and anxiety subscale and the NEO-FFI for personality traits. In addition, asthma duration, body mass index and FEV1 were measured. RESULTS: The prevalence of clinically significant depressive symptoms (9\% vs. 0 vs. 0\%; p = 0.009) and anxiety symptoms (19\% vs. 6.4 vs. 5.5\%; p = 0.01), was higher in patients with severe, prednisone-dependent asthma than in patients with severe non-prednisone dependent or mild-moderate asthma. Patients with prednisone-dependent asthma were respectively 3.4 (95\%CI: 1.0-10.8 p = 0.04) and 3.5 (95\%CI: 1.3-9.6 p = 0.01) times more likely to have significant depression symptoms and 1.6 (95\%CI: 0.7-3.7, p = 0.2) and 2.5 (95\%CI: 01.1-5.5, p = 0.02) times more likely to have symptoms of anxiety than patients with severe non-prednisone dependent or mild-moderate asthma. There were no differences found in personality traits between the 3 groups. CONCLUSION: Patients with severe, prednisone-dependent asthma have more often psychological distress as compared to patients with severe non-prednisone dependent or mild-moderate asthma. Copyright © 2014. Published by Elsevier Ltd. This article was published in Respir Med and referenced in Journal of Clinical & Cellular Immunology

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords