alexa AOAC International methods committee guidelines for validation of qualitative and quantitative food microbiological official methods of analysis.


Journal of Bacteriology & Parasitology

Author(s): Feldsine P, Abeyta C, Andrews WH AOAC Interna

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Abstract Responding to a need for a guide for conducting Official Method validation studies of microbiological methods, AOAC utilized the experience of three microbiologists who have been active in the field of method validation. In collaboration, a document was prepared which covered the following areas: terms and their definitions associated with the Official Methods program (e.g., reference methods, alternative methods, and ruggedness testing), protocols and validation requirements for qualitative methods versus those for quantitative methods, the concept of the precollaborative study, ruggedness testing, tests for significant differences, performance indicators, and the approval process. After its preparation, this document was reviewed by the members of the Methods Committee on Microbiology and Extraneous Materials and by members of the Official Methods Board. Herein is presented the approved version of that document.
This article was published in J AOAC Int and referenced in Journal of Bacteriology & Parasitology

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