alexa Applications of new sequencing technologies for transcriptome analysis.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Transcriptomics: Open Access

Author(s): Morozova O, Hirst M, Marra MA, Morozova O, Hirst M, Marra MA

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Abstract Transcriptome analysis has been a key area of biological inquiry for decades. Over the years, research in the field has progressed from candidate gene-based detection of RNAs using Northern blotting to high-throughput expression profiling driven by the advent of microarrays. Next-generation sequencing technologies have revolutionized transcriptomics by providing opportunities for multidimensional examinations of cellular transcriptomes in which high-throughput expression data are obtained at a single-base resolution. This article was published in Annu Rev Genomics Hum Genet and referenced in Transcriptomics: Open Access

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