alexa Are three sputum acid-fast bacillus smears necessary for discontinuing tuberculosis isolation?
Microbiology

Microbiology

Mycobacterial Diseases

Author(s): Mathew P, Kuo YH, Vazirani B, Eng RH, Weinstein MP

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Abstract To evaluate the efficacy of three sputum acid-fast bacillus (AFB) smears to rule out pulmonary tuberculosis, sputum AFB smear and culture results were analyzed at two university-affiliated teaching hospitals. The negative predictive value of the smear increased by only 0.2\% on days 2 and 3 each, indicating that in low-prevalence populations, there is limited value in requiring three negative sputum AFB smears before discontinuing tuberculosis isolation.
This article was published in J Clin Microbiol and referenced in Mycobacterial Diseases

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