Author(s): Lanier LL, Corliss B, Phillips JH
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Abstract NK cells express receptors for polymorphic MHC class I molecules that inhibit killing of potential target cells bearing appropriate class I allotypes. Here we review the membrane receptors on human NK cells that are known to initiate cell-mediated cytotoxicity and demonstrate regulation of these responses by the killer cell inhibitory (KIR) receptors.
This article was published in Immunol Rev
and referenced in Journal of Health & Medical Informatics