Author(s): Sakurai T, Nishimura T, Otake N, Xinsheng Y, Abe K,
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Abstract Two novel triterpenoid saponins with insulin-like activity, termed assamicin I and II, were isolated from the roots of Aesculus assamica Griff. and their structures were characterized as 1 and 2, respectively. They inhibited release of free fatty acids from epinephrine-treated rat adipocytes and enhanced glucose uptake into 3T3-L1 adipocytes.
This article was published in Bioorg Med Chem Lett
and referenced in Journal of Addiction Research & Therapy