Author(s): Marn A, Martnez Vidal JL, Egea Gonzalez FJ, Garrido Frenich A, Glass CR, , Marn A, Martnez Vidal JL, Egea Gonzalez FJ, Garrido Frenich A, Glass CR,
Abstract Share this page
Abstract New analytical methods based on liquid chromatography with electrospray tandem mass spectrometry (LC-MS/MS) have been developed and validated for assessing the exposure of greenhouse workers to acetamiprid. Both ambient (potential inhalation and dermal exposure) and internal dose (biological monitoring of urine samples) measurements were carried out. Potential inhalation exposure was assessed using Chromosorb 102 cartridges connected to air personal samplers. Potential dermal exposure was estimated by using whole body dosimetry. The measurement of actual exposure was done by analyzing the parent compound in urine samples of the applicators, after a solid-phase extraction (SPE) step. The methods showed a good accuracy (72-92\%), precision (2-13\%) and lower limits (few microg l(-1)). The validated approaches have been applied to assess potential and actual exposure of agricultural workers spraying acetamiprid in greenhouses. The results shown the need to wear personal protective equipment (suits) in order to reduce the absorbed dose of acetamiprid.
This article was published in J Chromatogr B Analyt Technol Biomed Life Sci
and referenced in Journal of Environmental & Analytical Toxicology