Author(s): Fonteneau JF, Guillerme JB, Tangy F, Grgoire M
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Abstract Attenuated measles viruses (MV) are assessed in clinical trials for their capacity to preferentially infect and kill tumor cells. We recently showed that MV-infected tumor cells are able to activate tumor antigen cross-presentation by myeloid and plasmacytoid dendritic cells. Thus, MV-based antitumor virotherapy may stimulate antitumor immune response.
This article was published in Oncoimmunology
and referenced in Journal of Clinical & Cellular Immunology