alexa [Autosomal dominant polycystic kidney disease (ADPKD). in Morocco. Multicenter study about 308 families].


Journal of Nephrology & Therapeutics

Author(s): Bourquia A Socit mar

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Abstract Autosomal dominant polycystic kidney disease (ADPKD) has aroused great interest these last years, especially after the discovery of the genes responsible for this disease. It remains a frequent cause of chronic renal failure (CRF). In this work we report the results of a multi-centre retrospective study. The data relates to 41 centres of nephrology and dialysis in Morocco, 308 Moroccan families and 420 observations. We have tried to determine the frequency of this pathology in Morocco, its complications and difficulties in taking care of it. The average age of the discovery of ADPKD was 46 +/- 3 years and the sex ratio was of 1.08. The ADPKD frequency among Moroccans who undergo dialysis was 6.5\%. Pain was the most frequent symptom which revealed the disease (21\%); while renal failure at different stages was found in 17\% of the patients and high blood pressure (HBP) in 11\%. The clinic diagnosis was confirmed by echography in 95\% of cases. The association with a hepatic cysts was found in 17.8\% of the cases. In addition, to HBR and urinary tract infection, the complications were largely dominated by renal chronic failure and the difficulties in taking care of it because of economic problems. Through this the authors discuss and report the profile and the prognostics of this infection in our society, with a special focus on the evolution of the renal function, the delay in the diagnosis and the management.
This article was published in Nephrologie and referenced in Journal of Nephrology & Therapeutics

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