Author(s): Ohene A
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Abstract Between January, 1994 and June, 1996 a survey of bacterial isolates from clinical specimens and their antimicrobial susceptibility was performed at the Komfo Anokye Teaching Hospital, Microbiology Department, Kumasi, Ghana. A total of 11,380 bacterial isolates were cultured from eight different specimens. The sites of origin were wounds 32.2\%, urine 28.1\%, ear, nose and throat 3.6\%, sputum 2.5\% and aspirates 2.5\%. Gram-negative bacteria accounted for 7955 (69.9\%) isolates, the main species were Escherichia coli 47.1\%, Pseudomonas spp. 16.8\%, Proteus spp 14.6\%, Klebsiella spp 10.2\%, Neisseria gonorrhoeae 4.2\%, Gram-positive bacteria contributed 3425 ((30.1\%) of isolates, with Staphylococcus aureus 54.6\% being the most predominant followed by Coagulase negative Staphylococcus 18.1\%, Streptococcus pneumoniae 13.7\% and Beta-haemolytic streptococci 4.1\%. Escherichia coli showed 88\% and 82\% resistance to ampicillin and cotrimoxazole respectively with 78\% being susceptible to gentamicin. Cefuroxime resistance in Gram-negative bacilli was 5\%. As much as 30.6\% and 21.7\% of Streptococcus pneumoniae isolates were resistant to Penicillin and chloramphenicol respectively. Ten per cent of Staphylococcus aureus strains were susceptible to penicillin and 18\% were resistant to flucloxacillin.
This article was published in East Afr Med J
and referenced in Journal of Antimicrobial Agents