Author(s): Andersch B, Lindell D, Dahln I, Brandberg A
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Abstract Intermittent treatment with an acid lactate gel (Lactal, ACO, Sweden) reduced symptoms of bacterial vaginosis (BV) and promoted the reestablishment of the normal vaginal flora of lactobacilli. Forty-two women seriously affected by recurrent BV were initially given acid gel (lactate gel, pH 3.8, 5 ml) to be inserted into the vagina daily for 7 consecutive days. Thereafter they entered into a double blind clinical trial and were treated prophylactically 3 days monthly for 6 months with either lactate gel or a placebo gel. Women treated with the lactate gel were clinically improved, i.e. no signs of BV in 88\% compared to 10\% in the placebo group (p less than 0.001). The vaginal lactobacilli flora was reestablished in 83\% of the lactate group and in 16\% of the placebo group. Local intermittent application of lactate gel was found to be free of side effects and is a preferable alternative to repeated treatments with antibiotics in patients with recurrent BV.
This article was published in Gynecol Obstet Invest
and referenced in Anatomy & Physiology: Current Research