Author(s): Muradin GS, Bosch JL, Stijnen T, Hunink MG
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Abstract PURPOSE: To perform a meta-analysis of long-term results of balloon dilation and stent implantation in the treatment of femoropopliteal arterial disease. MATERIALS AND METHODS: The English-language literature was searched for studies published between 1993 and 2000. Inclusion criteria for articles were presentation of long-term primary patency rates, standard errors (explicitly reported or derivable), and baseline characteristics of the study population. Two reviewers independently extracted data, and discrepancies were resolved by consensus. Primary patency rates were combined by using a technique that allows adjustment for differences across study populations. Analyses were adjusted for lesion type and clinical indication. RESULTS: Nineteen studies met the inclusion criteria, representing 923 balloon dilations and 473 stent implantations. Combined 3-year patency rates after balloon dilation were 61\% (standard error, 2.2\%) for stenoses and claudication, 48\% (standard error, 3.3\%) for occlusions and claudication, 43\% (standard error, 4.1\%) for stenoses and critical ischemia, and 30\% (standard error, 3.7\%) for occlusions and critical ischemia. The 3-year patency rates after stent implantation were 63\%-66\% (standard error, 4.1\%) and were independent of clinical indication and lesion type. Funnel plots demonstrated an asymmetric distribution of the data points associated with stent studies. CONCLUSION: Balloon dilation and stent implantation for claudication and stenosis yield similar long-term patency rates. For more severe femoropopliteal disease, the results of stent implantation seem more favorable. Publication bias could not be ruled out.
This article was published in Radiology
and referenced in Journal of Antivirals & Antiretrovirals