alexa Benign and malignant thyroid nodules: US differentiation--multicenter retrospective study.
Oncology

Oncology

Journal of Cancer Diagnosis

Author(s): WonJin Moon, So Lyung Jung, Jeong Hyun Lee, Dong Gyu Na, JungHwan Baek

Abstract Share this page

At ultrasonography (US), 10%–67% of adults have thyroid nodules, and nearly 50% of the population have thyroid nodules at autopsy (1–4). As determined at fine-needle aspiration cytology, 9.2%–14.8% of nodules identified at clinical examination are diagnosed as malignant (5–7). Thyroid US has been widely used to differentiate benign from malignant nodules and to guide fine-needle aspiration cytology for nodules suspected of being malignant (1,8). US features predictive of malignant nodules include the presence of microcalcifications, hypoechogenicity, and irregular margins, the absence of a halo, a predominantly solid composition, and an intranodular vascularity (5,6,9–14). Some investigators (5,15) suggest that a combination of these US findings provides better diagnostic accuracy than only one of these findings. However, considerable overlap between benign and malignant characteristics has been found in results of some studies (12,14). Sensitivity and specificity of the US findings for malignant thyroid nodules are also variable (1,5,9,11,16,17). Factors that may affect the findings reported in previous studies include the use of different US equipment, the experience of the radiologists (or physicians), and the different US criteria for identifying a malignancy. In addition to unavoidable interobserver variability during the US examination, there is also the problem of a nonstandardized lexicon for the characterization of thyroid nodules. The purpose of our study was to retrospectively evaluate the diagnostic accuracy of US criteria for the depiction of benign and malignant thyroid nodules by using tissue diagnosis as the reference standard.

This article was published in Radiology and referenced in Journal of Cancer Diagnosis

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords