alexa beta-Blockers in hypertension: is carvedilol different?
Biochemistry

Biochemistry

Biochemistry & Physiology: Open Access

Author(s): Messerli FH, Grossman E

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Abstract Most studies assessing the effects of beta-blockers were carried out with traditional, beta(1)-selective beta-blockers, such as metoprolol and atenolol. Pathophysiologic and pharmacologic studies have documented that not all beta-blockers are created equal. In particular, the pharmacologic and clinical profiles of the newer, vasodilating beta-blockers, such as carvedilol, have been shown to differ from those of the traditional beta-blockers. These differences, although relevant in the younger patient with hypertension, are particularly important in elderly patients in whom traditional beta-blockers may not be as effective or as well tolerated as the newer vasodilating agents. This article was published in Am J Cardiol and referenced in Biochemistry & Physiology: Open Access

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