Author(s): Boldrey EE
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Abstract A case of successfully treated Aspergillus endophthalmitis is presented. Treatment consisted of wide vitrectomy. At the end of surgery, 5 micrograms of amphoteracin B were injected into the center of the vitreous cavity, and an additional .75 mg was given subconjunctivally both at surgery and on the second postoperative day, at which time 2 mg of dexamethasone were also given subjunctivally. Systemic antifungal agents were not used. After 2 1/2 months, the second eye developed a similar metastatic infection from heart value vegetation. This case illustrates that use of wide vitrectomy and intravitreous antifungal agents alone can cure Aspergillus endophthalmitis and preserve useful vision.
This article was published in Retina
and referenced in Journal of Antivirals & Antiretrovirals