alexa Biological activities and volatile constituents of Daucus muricatus L. from Algeria.
Pharmaceutical Sciences

Pharmaceutical Sciences

Pharmaceutica Analytica Acta

Author(s): Bendiabdellah A, El Amine Dib M, Djabou N, Allali H, Tabti B,

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Abstract BACKGROUND: In order to find new bioactive natural products, the antimicrobial and antioxidant activities of essential oil components extracted from the separated organs of the Algerian medicinal and aromatic plant Daucus muricatus L. were studied. RESULTS: The chemical composition of essential oils obtained by hydrodistillation (HD) was investigated using Gas Chromatography-Retention Indices (GC-RI) and GC-Mass Spectrometry (GC-MS). Two types of essential oils were produced by D. muricatus: (i) The oil from roots is mainly composed by nonterpenic oxygenated compounds (59.8 g/100 g), and (ii) the aerial part oils (i.e., the leaves, stems, flowers, and umbels) was mainly composed by terpenic hydrocarbon compounds (62.3-72.2 g/100 g). The chemical composition of the volatile fraction isolated from different organs of Daucus muricatus were studied by HS-SPME/GC-RI and GC-MS after optimization of Solid Phase MicroExtraction parameters. For all organs studied, the main volatiles emitted by the plant were hydrocarbon compounds (60.7-82.2 g/100 g). Only quantitative differences between the volatiles of the separated organs studied were observed. In addition, the activity of the oil of D. muricatus against eight bacterial strains and one yeast was investigated. The oil from roots revealed active against S. aureus, while the essential oil obtained from the aerial parts was active against the yeast C. albicans. CONCLUSIONS: Daucus muricatus essential oil seems be a promising source of natural products with potential antimicrobial activity.
This article was published in Chem Cent J and referenced in Pharmaceutica Analytica Acta

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