alexa Bioprinting toward organ fabrication: challenges and future trends.
Dentistry

Dentistry

Journal of Oral Hygiene & Health

Author(s): Ozbolat IT, Yu Y

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Abstract Tissue engineering has been a promising field of research, offering hope for bridging the gap between organ shortage and transplantation needs. However, building three-dimensional (3-D) vascularized organs remains the main technological barrier to be overcome. Organ printing, which is defined as computer-aided additive biofabrication of 3-D cellular tissue constructs, has shed light on advancing this field into a new era. Organ printing takes advantage of rapid prototyping (RP) technology to print cells, biomaterials, and cell-laden biomaterials individually or in tandem, layer by layer, directly creating 3-D tissue-like structures. Here, we overview RP-based bioprinting approaches and discuss the current challenges and trends toward fabricating living organs for transplant in the near future. This article was published in IEEE Trans Biomed Eng and referenced in Journal of Oral Hygiene & Health

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