alexa Blood-based protein biomarker panel for the detection of colorectal cancer.
Gastroenterology

Gastroenterology

Journal of Gastrointestinal & Digestive System

Author(s): Kim Y C Fung, Bruce Tabor

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The majority of colorectal cancer (CRC) cases are preventable by early detection and removal of precancerous polyps. Even though CRC is the second most common internal cancer in Australia, only 30 per cent of the population considered to have risk factors participate in stool-based test screening programs. Evidence indicates a robust, blood-based, diagnostic assay would increase screening compliance. A number of potential diagnostic blood-based protein biomarkers for CRC have been reported, but all lack sensitivity or specificity for use as a stand-alone diagnostic. The aim of this study was to identify and validate a panel of protein-based biomarkers in independent cohorts that could be translated to a reliable, non-invasive blood-based screening test.

This article was published in PLoS One and referenced in Journal of Gastrointestinal & Digestive System

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