alexa Bovine lactoferrin inhibits adenovirus infection by interacting with viral structural polypeptides.


Journal of Cancer Science & Therapy

Author(s): Pietrantoni A, Di Biase AM, Tinari A, Marchetti M, Valenti P,

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Abstract We recently demonstrated that lactoferrin, an antimicrobial glycoprotein, can inhibit adenovirus infection by competing for common glycosaminoglycan receptors. This study further characterizes the antiadenovirus activity of the protein, thus demonstrating that lactoferrin neutralizes infection by binding to adenovirus particles and that its targets are viral III and IIIa structural polypeptides.
This article was published in Antimicrob Agents Chemother and referenced in Journal of Cancer Science & Therapy

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