alexa Breast carcinoma in young females below the age of 40 years: A histopathological perspective.


Journal of Carcinogenesis & Mutagenesis

Author(s): Thangjam S, Laishram RS, Debnath K

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Abstract BACKGROUND: Breast cancer among young women is a rare pathology, but is known to have a more aggressive behavior and poorer outcome. AIMS: The objective of this study was to evaluate the clinicopathological characteristics of breast carcinoma below 40 years in comparison to that over 40 years in Manipur, India. SETTINGS AND DESIGN: This retrospective study from the period of January 2005-December 2010 was conducted in the Department of Pathology, Regional Institute of Medical Sciences, Imphal, Manipur. MATERIALS AND METHODS: All cases of mastectomy specimens of carcinoma breast from the period of January 2005-December 2010 were included in the study. Clinical and histopathological data of all cases were reviewed and correlated. RESULTS: A total of 507 mastectomy specimens were received, among which, 160 cases (31.56\%) were below 40 years; whereas 347 cases (68.44\%) were above 40 years of age. Stage III was the commonest stage (47\% versus 18\%) in the younger group; while in the older group, Stage II was the commonest (64\% versus 34\%). CONCLUSION: This study shows that young females with breast cancer have higher stage of tumor.
This article was published in South Asian J Cancer and referenced in Journal of Carcinogenesis & Mutagenesis

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