Author(s): Hla T, Kolesnick R
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Abstract A substantive literature has accumulated implicating sphingolipids, in particular ceramides, as mediators of insulin resistance in metabolic syndrome. Thanks to recent technical advances in mouse genetics and lipidomics, two independent laboratories identify the same sphingolipid, C16:0-ceramide, as principal mediator of obesity-related insulin resistance (Turpin et al., 2014; Raichur et al., 2014). Copyright © 2014 Elsevier Inc. All rights reserved.
This article was published in Cell Metab
and referenced in Journal of Proteomics & Bioinformatics