alexa Caged ceramide 1-phosphate analogues: synthesis and properties.


Journal of Membrane Science & Technology

Author(s): Lankalapalli RS, Ouro A, Arana L, GmezMuoz A, Bittman R

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Abstract Sphingolipid phosphate analogues bearing 7-(diethylamino)coumarin (DECM) and 4-bromo-5-hydroxy-2-nitrobenzhydryl (BHNB) groups in a photolabile ester bond were synthesized. The ability of the "caged" ceramide 1-phosphate analogues to release the bioactive parent molecule upon irradiation at 400-500 nm was demonstrated by stimulation of macrophage cell proliferation.
This article was published in J Org Chem and referenced in Journal of Membrane Science & Technology

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