alexa Capillary gas chromatographic-mass spectrometric determination of buspirone in plasma.
Pharmaceutical Sciences

Pharmaceutical Sciences

Pharmaceutica Analytica Acta

Author(s): Gammans RE, Kerns EH, Bullen WW

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Abstract Methods for determining buspirone plus a deuterated analogue and for buspirone alone in plasma samples are described. Analytes are prepared from plasma by liquid extraction into n-butyl chloride and subsequent back-extraction clean-up steps. Instrumental analysis involves selected-ion monitoring gas chromatography-mass spectrometry with fused-silica capillary chromatography. Quantification is in the range 0.05-10 ng/ml with acceptable accuracy and precision.
This article was published in J Chromatogr and referenced in Pharmaceutica Analytica Acta

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