alexa Carcinogenic activity of condensate from coloquint seeds (Citrullus colocynthis) after chronic epicutaneous administration to mice.


Molecular Biology: Open Access

Author(s): Habs M, Jahn SA, Schmhl D

Abstract Share this page

Abstract In the Sahelian countries coloquint seed tar is used in traditional medicine. A condensate from the seed of Citrullus colocynthis was obtained in a camel nomad settlement. It contained a large number of polycyclic aromatic hydrocarbons, including known carcinogens [e.g., benzo(a)pyrene, benz(a)anthracene, benzo(b)fluoranthene, benzo(j)fluoranthene]. The dose-related carcinogenic activity of this condensate was established after chronic epicutaneous application to mouse skin. We conclude that the manufacture and use of coloquint tar and related compounds may involve a health hazard and could lead to the development of cancer.
This article was published in J Cancer Res Clin Oncol and referenced in Molecular Biology: Open Access

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version