Author(s): Podratz KC, Symmonds RE, Taylor WF, Williams TJ, Podratz KC, Symmonds RE, Taylor WF, Williams TJ
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Abstract The treatment of 224 patients with invasive squamous cell carcinoma of the vulva over a 20-year interval at the Mayo Clinic resulted in an overall survival rate of 75\%, compared with 89\% for age-matched controls. For patients with stage I disease, 5-year survival was 90\%; for those with stages II, III, and IV, it was 81, 68, and 20\%, respectively. A precipitous decline in survival rates was noted when metastases to regional nodes were encountered, when lesion size was more than 3 cm, and when histologic dedifferentiation exceeded grade 2. Incorrect clinical staging efforts were observed in 25\% of the cases, so the necessity for surgical staging was apparent.
This article was published in Obstet Gynecol
and referenced in Journal of Cancer Clinical Trials